Synthesis of a bicyclic oxo-γ-lactam from a simple caprolactam derivative
نویسندگان
چکیده
منابع مشابه
A Simple Method for Synthesis of γ-Aluminum Oxide Nanostructure Using PEG as a Neutral Surfactant
Nano-sized γ-Al2O3 was synthesized successfully by a simple method using Al2(SO4)3·18H2O as aluminium source and in the presence of polyethylene glycol (PEG 2000). FTIR spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to characterize the structure and morphology of synthesized powder. The results showed that PEG playe...
متن کاملA Simple Method for Synthesis of γ-Aluminum Oxide Nanostructure Using PEG as a Neutral Surfactant
Nano-sized γ-Al2O3 was synthesized successfully by a simple method using Al2(SO4)3·18H2O as aluminium source and in the presence of polyethylene glycol (PEG 2000). FTIR spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to characterize the structure and morphology of synthesized powder. The results showed that PEG playe...
متن کاملp-Nitrophenyl carbonate promoted ring-opening reactions of DBU and DBN affording lactam carbamates
The amidine bases DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) and DBN (1,5-diazabicyclo[4.3.0]non-5-ene) display nucleophilic behaviour towards highly electrophilic p-nitrophenyl carbonate derivatives with ring opening of the bicyclic ring to form corresponding substituted ε-caprolactam and γ-lactam derived carbamates. This simple method presents a unified strategy to synthesize structurally diver...
متن کاملST7612AA1, a thioacetate-ω(γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors.
A systematic study of medicinal chemistry aimed at identifying a new generation of HDAC inhibitors, through the introduction of a thiol zinc-binding group (ZBG) and of an amide-lactam in the ω-position of the polyethylene chain of the vorinostat scaffold, allowed the selection of a new class of potent pan-HDAC inhibitors (pan-HDACis). Simple, highly versatile, and efficient synthetic approaches...
متن کاملa simple method for synthesis of γ-aluminum oxide nanostructure using peg as a neutral surfactant
nano-sized γ-al2o3 was synthesized successfully by a simple method using al2(so4)3·18h2o as aluminium source and in the presence of polyethylene glycol (peg 2000). ftir spectroscopy, x-ray diffraction (xrd), scanning electron microscope (sem) and transmission electron microscope (tem) were used to characterize the structure and morphology of synthesized powder. the results showed that peg playe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: New Journal of Chemistry
سال: 2017
ISSN: 1144-0546,1369-9261
DOI: 10.1039/c7nj02348k